60576-13-8
60576-13-8
Chemical Structure
Piketoprofen
- CAS No.: 60576-13-8
- Formula:C22H20N2O2
- Molecular Weight:344.41
IUPAC Name: 2-(3-benzoylphenyl)-N-(4-methylpyridin-2-yl)propanamide
InChIKey: ASFKKFRSMGBFRO-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=CC(C)=C1)C(C)C2=CC=CC(C(C3=CC=CC=C3)=O)=C2
Biological Activity: Piketoprofen is a non-steroidal anti-inflammatory reagent that can be used as a cream preparation for the study of soft tissue rheumatism. Piketoprofen-amide is a prodrug of COX-2 inhibitor[1][2].
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Piketoprofen | 99.54% | Piketoprofen is a non-steroidal anti-inflammatory reagent that can be used as a cream preparation for the study of soft tissue rheumatism. Piketoprofen-amide is a prodrug of COX-2 inhibitor. | ||||||||||||||||||||
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Piketoprofen (Standard) | ≥98% | Piketoprofen (Standard) is the analytical standard of Piketoprofen. This product is intended for research and analytical applications. Piketoprofen is a non-steroidal anti-inflammatory reagent that can be used as a cream preparation for the study of soft tissue rheumatism. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-Z8792Ketoprofen impurity 5 -
Similarity Score 0.64
HY-B0227Ketoprofen -
Similarity Score 0.64
HY-B0227S3Ketoprofen-13C6 -
Similarity Score 0.64
HY-B2137RS-(+)-Ketoprofen (Standard) -
Similarity Score 0.64
HY-W322573(R)-Ketoprofen -
Similarity Score 0.63
HY-153326Ketoprofen impurity 11 -
Similarity Score 0.63
HY-167630Ketoprofen sodium -
Similarity Score 0.62
HY-W505177Ketoprofen impurity 10 -
Similarity Score 0.60
HY-156792RIOK2-IN-1 -
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References
- [1]. Chen W, et al. New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases. Mol Med. 2021 Sep 30;27(1):123. [Content Brief]
- [2]. Burgos A, et al. Double-blind, double-dummy comparative study of local action transcutaneous flurbiprofen (flurbiprofen LAT) versus piketoprofen cream in the treatment of extra-articular rheumatism[J]. Clinical Drug Investigation, 2001, 21: 95-102.
