62182-86-9
62182-86-9
Chemical Structure
13-Dihydrocarminomycin
- CAS No.: 62182-86-9
- Formula:C26H29NO10
- Molecular Weight:515.51
IUPAC Name: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)-7,8,9,10-tetrahydrotetracene-5,12-dione
InChIKey: YXBSCYMMPXQFDS-XELZYMDQSA-N
SMILES: OC1=C(C2=C(C3=C1C[C@](O)(C[C@@H]3O[C@H]4C[C@@H]([C@@H]([C@@H](O4)C)O)N)C(C)O)O)C(C5=C(C2=O)C(O)=CC=C5)=O
Biological Activity: 13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity[1][2].
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13-Dihydrocarminomycin | 13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity. | |||||||||||||||||||||
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References
- [1]. Yoshimoto A, et al. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5. J Antibiot (Tokyo). 1993 Jan;46(1):56-64. [Content Brief]
- [2]. Poteshnykh AV, et al. Determination of carminomycin and its basic metabolite 13-dihydrocarminomycin by a highly efficient liquid chromatographic method with a fluorescent detector. Antibiotiki. 1982 Nov;27(11):820-3. [Content Brief]
