13-Dihydrocarminomycin
13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity.
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- CAS 番号: 62182-86-9
- 分子式: C26H29NO10
- 分子量:515.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
13-Dihydrocarminomycin (compound D788-12; 0-1 mM; 48 h) inhibits the growth of L1210 cells, with an IC50 value of 0.06 µg/mL (120 µM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L1210 cells
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Concentration:0-1 mM
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Incubation Time:48 h
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Result:Suppressed cell growth (IC50 = 0.06 µg/mL or 120 µM).
化学情報
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CAS 番号 62182-86-9
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分子量 515.51
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分子式 C26H29NO10
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SMILES
OC1=C(C2=C(C3=C1C[C@](O)(C[C@@H]3O[C@H]4C[C@@H]([C@@H]([C@@H](O4)C)O)N)C(C)O)O)C(C5=C(C2=O)C(O)=CC=C5)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yoshimoto A, et al. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5. J Antibiot (Tokyo). 1993 Jan;46(1):56-64. [Content Brief]
[2]. Poteshnykh AV, et al. Determination of carminomycin and its basic metabolite 13-dihydrocarminomycin by a highly efficient liquid chromatographic method with a fluorescent detector. Antibiotiki. 1982 Nov;27(11):820-3. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
13-Dihydrocarminomycin 関連分類
HY-135176 関連分類
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