13-Dihydrocarminomycin
13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity.
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- CAS No.: 62182-86-9
- Formule: C26H29NO10
- Masse moléculaire:515.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Activité biologique
Description
In Vitro
13-Dihydrocarminomycin (compound D788-12; 0-1 mM; 48 h) inhibits the growth of L1210 cells, with an IC50 value of 0.06 µg/mL (120 µM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L1210 cells
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Concentration:0-1 mM
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Incubation Time:48 h
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Result:Suppressed cell growth (IC50 = 0.06 µg/mL or 120 µM).
Chemical Information
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CAS No. 62182-86-9
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Masse moléculaire 515.51
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Formule C26H29NO10
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SMILES
OC1=C(C2=C(C3=C1C[C@](O)(C[C@@H]3O[C@H]4C[C@@H]([C@@H]([C@@H](O4)C)O)N)C(C)O)O)C(C5=C(C2=O)C(O)=CC=C5)=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Yoshimoto A, et al. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5. J Antibiot (Tokyo). 1993 Jan;46(1):56-64. [Content Brief]
[2]. Poteshnykh AV, et al. Determination of carminomycin and its basic metabolite 13-dihydrocarminomycin by a highly efficient liquid chromatographic method with a fluorescent detector. Antibiotiki. 1982 Nov;27(11):820-3. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
13-Dihydrocarminomycin Related Classifications
HY-135176 Related Classifications
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