623163-52-0
Chemical Structure
IMDNQ1
- CAS No.: 623163-52-0
- Formula:C14H8ClNO4
- Molecular Weight:289.67
IUPAC Name: 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)pyrrolidine-2,5-dione
InChIKey: GYQSWJNGTWVFOL-UHFFFAOYSA-N
SMILES: O=C1C(Cl)=C(C(=O)C=2C=CC=CC12)N3C(=O)CCC3=O
Biological Activity: IMDNQ1 is a Trypanosoma cruzi inhibitor derived from 1,4-naphthoquinone substituted with cyclic imide. IMDNQ1 effectively inhibits the proliferation of Trypanosoma cruzi epimastigotes, while also reducing the viability of mouse fibroblasts. The selectivity index between the antiproliferative activity and cytotoxicity of IMDNQ1 is 60.25, indicating a certain level of safety. IMDNQ1 can be widely used in studies related to Chagas disease[1][2].
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IMDNQ1 | IMDNQ1 is a Trypanosoma cruzi inhibitor derived from 1,4-naphthoquinone substituted with cyclic imide. IMDNQ1 effectively inhibits the proliferation of Trypanosoma cruzi epimastigotes, while also reducing the viability of mouse fibroblasts. The selectivity index between the antiproliferative activity and cytotoxicity of IMDNQ1 is 60.25, indicating a certain level of safety. IMDNQ1 can be widely used in studies related to Chagas disease. | |||||||||||||||||||||
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Keywords
