63-92-3
63-92-3
Chemical Structure
Phenoxybenzamine hydrochloride
- CAS No.: 63-92-3
- Formula:C18H23Cl2NO
- Molecular Weight:340.29
IUPAC Name: N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine hydrochloride
InChIKey: VBCPVIWPDJVHAN-UHFFFAOYSA-N
SMILES: CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
Biological Activity: Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Phenoxybenzamine hydrochloride | 99.53% | Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity. | ||||||||||||||||||||
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Phenoxybenzamine hydrochloride (Standard) | 99.53% | Phenoxybenzamine (hydrochloride) (Standard) is the analytical standard of Phenoxybenzamine (hydrochloride). This product is intended for research and analytical applications. Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity. | ||||||||||||||||||||
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Phenoxybenzamine (benzyl-2,3,4,5,6-d5) hydrochloride | Phenoxybenzamine (benzyl-2,3,4,5,6-d5) (hydrochloride) is the deuterium labeled Phenoxybenzamine hydrochloride. Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity. | |||||||||||||||||||||
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Phenoxybenzamine-d5 hydrochloride | Phenoxybenzamine-d5 (hydrochloride) is the deuterium labeled Phenoxybenzamine hydrochloride. Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity. | |||||||||||||||||||||
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Dibenamine hydrochloride | 99.32% | Dibenamine hydrochloride is a competitive and irreversible adrenergic blocking agent and is known to modify the pharmacological effects of epinephrine. Dibenamine hydrochloride cause a significant increase in the rate of destruction of I-epinephrine in the mouse. | ||||||||||||||||||||
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Tesmilifene hydrochloride | Tesmilifene hydrochloride is an antihistamine agent and a chemical sensitizer. Tesmilifene hydrochloride targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene hydrochloride overcomes multidrug resistance. | |||||||||||||||||||||
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Solpecainol | Solpecainol is an antiarrhythrmic compound. Solpecainol is a polarisation inhibitor. | |||||||||||||||||||||
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Dibenamine | Dibenamine is an alpha-adrenergic antagonist that exhibits the ability to block both basal and histamine-stimulated gastric acid secretion, making it therapeutically relevant in conditions involving excessive gastric acid production. | |||||||||||||||||||||
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Phenoxybenzamine | Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity. | |||||||||||||||||||||
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Phenoxybenzamine-d5 | Phenoxybenzamine-d5 is the deuterium labeled Phenoxybenzamine. Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity. | |||||||||||||||||||||
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N,N-Bis(phenylmethyl)-L-serine methyl ester | N,N-Bis(phenylmethyl)-L-serine methyl ester is a biochemical assay reagent used in peptide chemistry. | |||||||||||||||||||||
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References
- [1]. Habbe N, et al. Urapidil in the preoperative treatment of pheochromocytomas: a safe and cost-effective method. World J Surg. 2013 May;37(5):1141-6. [Content Brief]
- [2]. Lin XB, et al. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8. [Content Brief]
