634207-55-9
634207-55-9
Chemical Structure
8-Chloro-2’-O-methyl adenosine
- CAS No.: 634207-55-9
- Formula:C11H14ClN5O4
- Molecular Weight:315.71
IUPAC Name: (2R,3R,4R,5R)-5-(6-amino-8-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
InChIKey: IXTQMSFHXDXWKT-KQYNXXCUSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N(C(Cl)=N2)C3=C2C(N)=NC=N3)O[C@@H]1CO
Biological Activity: 8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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8-Chloro-2’-O-methyl adenosine | 8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
