648895-38-9
Chemical Structure
Bapineuzumab
Synonym(s): AAB-001
- CAS No.: 648895-38-9
- Formula:N/A
- Molecular Weight:(144.5 kDa)
IUPAC Name: tert-butyl (5-iodopyrimidin-2-yl)carbamate
SMILES: [Bapineuzumab]
Biological Activity: Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab is a humanized IgG1 that recognizes the N terminus of Aβ cleared plaques from the brains. Bapineuzumab can be used for the research of Alzheimer’s disease (AD)[1][2].
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Bapineuzumab | 96.62% | Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab is a humanized IgG1 that recognizes the N terminus of Aβ cleared plaques from the brains. Bapineuzumab can be used for the research of Alzheimer’s disease (AD). | ||||||||||||||||||||
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- [1]. Stephen Salloway, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med. 2014 Jan 23;370(4):322-33. [Content Brief]
- [2]. Fuller, J. P., et al., (2015). Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies. Acta neuropathologica, 130(5), 699–711. [Content Brief]
Keywords