65086-32-0
Chemical Structure
Nystatin A2
- CAS No.: 65086-32-0
- Formula:C47H75NO16
- Molecular Weight:910.10
IUPAC Name: (1R,3S,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27Z,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,7,9,11,17,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
InChIKey: RALQCAVZSAUESR-FJBFTIJASA-N
SMILES: OC([C@H]1[C@@]2([H])O[C@@](C[C@@H]1O)(C[C@H](CCC[C@H](C[C@H](C[C@H](CC(O[C@H]([C@@H]([C@@H]([C@H](/C=C/C=C/CC/C=C/C=C\C=C\C=C\[C@@H](C2)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O)C)O)C)C)=O)O)O)O)O)O)=O
Biological Activity: Nystatin A2 is an active component of antifungal agent, Nystatin (HY-17409). Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma[1][2].
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Nystatin A2 | Nystatin A2 is an active component of antifungal agent, Nystatin (HY-17409). Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. | |||||||||||||||||||||
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References
- [1]. Filipa Sousa, et al. Reviving the interest in the versatile drug nystatin: A multitude of strategies to increase its potential as an effective and safe antifungal agent. Adv Drug Deliv Rev. 2023 Aug:199:114969. [Content Brief]
- [2]. Ellepola AN, et al. Adhesion of oral Candida species to human buccal epithelial cells following brief exposure to nystatin. Oral Microbiol Immunol. 1999 Dec;14(6):358-63. [Content Brief]
