66648-50-8
Chemical Structure
Ethyl trans-caffeate
- CAS No.: 66648-50-8
- Formula:C11H12O4
- Molecular Weight:208.21
IUPAC Name: ethyl (E)-3-(3,4-dihydroxyphenyl)acrylate
InChIKey: WDKYDMULARNCIS-GQCTYLIASA-N
SMILES: O=C(/C=C/C1=CC=C(C(O)=C1)O)OCC
Biological Activity: Ethyl trans-caffeate is a matrix metalloproteinase inhibitor (MMP-1, MMP-2, MMP-9). Ethyl trans-caffeate can be isolated from Artemisia aucheri. Ethyl trans-caffeate binds to the SARS-CoV-2 main protease by forming a hydrogen bond with Thr190. The PMK extract of Pandanus tectorius fruit containing Ethyl trans-caffeate inhibits HMG-CoA reductase activity. Ethyl trans-caffeate can be used in research on COVID-19 and atherosclerosis[1][2][3].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Ethyl trans-caffeate | 98.0% | Ethyl trans-caffeate is a matrix metalloproteinase inhibitor (MMP-1, MMP-2, MMP-9). Ethyl trans-caffeate can be isolated from Artemisia aucheri. Ethyl trans-caffeate binds to the SARS-CoV-2 main protease by forming a hydrogen bond with Thr190. The PMK extract of Pandanus tectorius fruit containing Ethyl trans-caffeate inhibits HMG-CoA reductase activity. Ethyl trans-caffeate can be used in research on COVID-19 and atherosclerosis. | ||||||||||||||||||||
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References
- [1]. Kanbarkar N. Matrix metalloproteinase inhibitors identified from Camellia sinensis for COVID-19 prophylaxis: an in silico approach: N. Kanbarkar, S. Mishra. Advances in Traditional Medicine. 2021 Mar;21(1):173-88.
- [2]. Andriani Y, Pangestika I, Oksal E, et al. Anti-atherosclerosis potency of Pandanus tectorius fruit rich by trangeretin and ethyl trans-caffeate, and their cytotoxicity against HepG2 cell line[C]//IOP Conference Series: Materials Science and Engineering. IOP Publishing, 2019, 509(1): 012155.
- [3]. Medrano-Padial C. Bioaccessible Phenolic Alkyl Esters of Wine Lees Decrease COX-2-Catalyzed Lipid Mediators of Oxidative Stress and Inflammation in a Time-Dependent Manner. Journal of agricultural and food chemistry. 2024 Aug 15;72(34):19016.
