668467-91-2
668467-91-2
Chemical Structure
LDN-57444
- CAS No.: 668467-91-2
- Formula:C17H11Cl3N2O3
- Molecular Weight:397.64
IUPAC Name: (Z)-3-(acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)indolin-2-one
InChIKey: OPQRFPHLZZPCCH-PGMHBOJBSA-N
SMILES: O=C1N(CC2=CC(Cl)=CC=C2Cl)C3=C(C=C(Cl)C=C3)/C1=N/OC(C)=O
Biological Activity: LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1), with an IC50 of 0.88 μM and a Ki of 0.40 μM; LDN-57444 also suppresses UCH-L3 activity, with an IC50 of 25 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LDN-57444 | 99.21% | LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1), with an IC50 of 0.88 μM and a Ki of 0.40 μM; LDN-57444 also suppresses UCH-L3 activity, with an IC50 of 25 μM. | ||||||||||||||||||||
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