UCH-L1
UCH-L1, also known as PGP9.5 and encoded by the UCHL1 gene, is a cysteine protease of the ubiquitin C-terminal hydrolase family and one of the most abundant proteins in the brain, where it constitutes an estimated 1-2 percent of soluble neuronal protein. The enzyme hydrolyzes small C-terminal adducts of ubiquitin to generate free monoubiquitin and maintains ubiquitin homeostasis in neurons. Dimerization confers an E3 ligase-like activity reported for this protein. UCHL1 mutations, including the I93M substitution, have been linked to familial Parkinson disease, and the protein is a widely used marker for neurons, neuroendocrine cells and their tumors.
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UCH-L1 Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
