67027-56-9
Chemical Structure
(±)-Meclonazepam
Synonym(s): (±)-Ro 11-3128; (±)-Ro 11-3128/002
- CAS No.: 67027-56-9
- Formula:C16H12ClN3O3
- Molecular Weight:329.74
InChIKey: LMUVYJCAFWGNSY-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C(C3=C(Cl)C=CC=C3)=NC1C)C=C([N+]([O-])=O)C=C2
Biological Activity: (±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect[1]. Meclonazepam exhibits antischistosomal activity against S. mansoni[2].
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(±)-Meclonazepam | (±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam exhibits antischistosomal activity against S. mansoni. | |||||||||||||||||||||
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- [1]. T U Järbe, et al. Cueing effects of anxiolytic benzodiazepines (DZP and Ro 11-3128): stereospecificity and antagonism by the convulsant benzodiazepine Ro 5-3663. Psychopharmacology (Berl). 1988;94(4):501-6. [Content Brief]
- [2]. L Pica-Mattoccia, et al. Praziquantel and the benzodiazepine Ro 11-3128 do not compete for the same binding sites in schistosomes. Parasitology. 2008 Jan;135(Pt 1):47-54. [Content Brief]
Keywords