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Cat. No.: HY-169445

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(±)-Meclonazepam

(Synonyms: (±)-Ro 11-3128; (±)-Ro 11-3128/002)

(±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam exhibits antischistosomal activity against S. mansoni.

For research use only. We do not sell to patients.

CAS No.: 67027-56-9
Formula: C₁₆H₁₂ClN₃O₃
Molecular Weight:329.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

(±)-Meclonazepam Chemical Structure

CAS No.: 67027-56-9

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Description

(±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect^[1]. Meclonazepam exhibits antischistosomal activity against S. mansoni^[2].

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Chemical Information

CAS No. 67027-56-9
Molecular Weight 329.74
Formula C₁₆H₁₂ClN₃O₃
SMILES

O=C1NC2=C(C(C3=C(Cl)C=CC=C3)=NC1C)C=C([N+]([O-])=O)C=C2
Synonyms

(±)-Ro 11-3128; (±)-Ro 11-3128/002
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. T U Järbe, et al. Cueing effects of anxiolytic benzodiazepines (DZP and Ro 11-3128): stereospecificity and antagonism by the convulsant benzodiazepine Ro 5-3663. Psychopharmacology (Berl). 1988;94(4):501-6. [Content Brief]

[2]. L Pica-Mattoccia, et al. Praziquantel and the benzodiazepine Ro 11-3128 do not compete for the same binding sites in schistosomes. Parasitology. 2008 Jan;135(Pt 1):47-54. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(±)-Meclonazepam

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(±)-Meclonazepam Related Classifications

HY-169445 Related Classifications