68171-52-8
Chemical Structure
Linoleoyl ethanolamide
Synonym(s): Linoleic acid monoethanolamide
- CAS No.: 68171-52-8
- Formula:C20H37NO2
- Molecular Weight:323.51
IUPAC Name: (9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dienamide
InChIKey: KQXDGUVSAAQARU-HZJYTTRNSA-N
SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(NCCO)=O
Biological Activity: Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Linoleoyl ethanolamide | 99.98% | Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time. | ||||||||||||||||||||
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Linoleoyl ethanolamide-d4 | 99.15% | Linoleoyl ethanolamide-d4 is a deuterated labeled Linoleoyl ethanolamide. Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time. The product specifications provided below refer solely to the active content of Linoleoyl ethanolamide-d4. |
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Similarity Score 0.95
HY-16903811(Z),14(Z)-Eicosadienoic acid ethanolamide -
Similarity Score 0.92
HY-127061Palmitoleoyl ethanolamide -
Similarity Score 0.92
HY-113070Dihomo-γ-Linolenoyl Ethanolamide -
Similarity Score 0.91
HY-N16018C17:1 Anandamide -
Similarity Score 0.91
HY-107542SOleoylethanolamide-d4 -
Similarity Score 0.90
HY-162298γ-Linolenoyl monoethanolamide -
Similarity Score 0.90
HY-107542Oleoylethanolamide -
Similarity Score 0.90
HY-N16027C18:1 Anandamide -
Similarity Score 0.90
HY-166206(9Z,11E)-Octadecadien ethanolamide -
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References
- [1]. Wang X, et al. X. Synthesis of linoleoyl ethanolamide. J Oleo Sci. 2013;62(6):427-433. [Content Brief]
- [2]. Lin S, et al. Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. J Med Chem. 1998;41(27):5353-5361. [Content Brief]
