681816-57-9
Chemical Structure
ATI22-107
- CAS No.: 681816-57-9
- Formula:C31H32Cl2N4O8
- Molecular Weight:659.51
IUPAC Name: dimethyl 2-((2-(2-(2-chloro-4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenoxy)acetamido)ethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: IEWHOLAJSCSUMW-UHFFFAOYSA-N
SMILES: O=C(C1=C(COCCNC(COC2=CC=C(C(CC3)=NNC3=O)C=C2Cl)=O)NC(C)=C(C(OC)=O)C1C4=CC=CC=C4Cl)OC
Biological Activity: ATI22-107 is a dual-pharmacophore compound designed to simultaneously inhibit cardiac phosphodiesterase (PDE-III) and L-type calcium channels (LTCC), with activity that has specific effects on calcium cycling and contractility in cat ventricular myocytes and trabeculae.
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ATI22-107 | ATI22-107 is a dual-pharmacophore compound designed to simultaneously inhibit cardiac phosphodiesterase (PDE-III) and L-type calcium channels (LTCC), with activity that has specific effects on calcium cycling and contractility in cat ventricular myocytes and trabeculae. | |||||||||||||||||||||
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Keywords