68642-64-8
Chemical Structure
Kojic amine
- CAS No.: 68642-64-8
- Formula:C6H7NO3
- Molecular Weight:141.13
IUPAC Name: 2-(aminomethyl)-5-hydroxy-4H-pyran-4-one
InChIKey: AULIQBZSRZXJJU-UHFFFAOYSA-N
SMILES: O=C1C=C(OC=C1O)CN
Biological Activity: Kojic amine is an orally active γ-aminobutyric acid (GABA) analog. Kojic amine acts as a GABA mimic that inhibits sodium-independent [3H]GABA binding to rat brain cell membranes. Kojic amine reduces flexor spasms in chronic spinal rat and cat models. Kojic amine prevents tonic extensor convulsions in mice. Kojic amine produces a transient, dose-dependent analgesic effect in the mouse hot-plate test. Kojic amine can be used in research related to skeletal muscle spasm, epilepsy and analgesia[1][2]
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Kojic amine | Kojic amine is an orally active γ-aminobutyric acid (GABA) analog. Kojic amine acts as a GABA mimic that inhibits sodium-independent [3H]GABA binding to rat brain cell membranes. Kojic amine reduces flexor spasms in chronic spinal rat and cat models. Kojic amine prevents tonic extensor convulsions in mice. Kojic amine produces a transient, dose-dependent analgesic effect in the mouse hot-plate test. Kojic amine can be used in research related to skeletal muscle spasm, epilepsy and analgesia
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Keywords
