690215-80-6
690215-80-6
Chemical Structure
O-GlcNAcase-IN-5
- CAS No.: 690215-80-6
- Formula:C27H27N3O7S
- Molecular Weight:537.58
InChIKey: WONPAKDTWXTTLP-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C=C1C3=CSC(NC(CCC(NCCC4=CC=C(C(OC)=C4)OC)=O)=O)=N3)C=CC(OC)=C2
Biological Activity: O-GlcNAcase-IN-5 (Compound 1) is a selective O-GlcNAcase inhibitor. O-GlcNAcase-IN-5 can prevent the enzyme from removing the O-GlcNAc modification on tau protein, thus avoiding excessive phosphorylation of tau protein. O-GlcNAcase-IN-5 can be used for the research of Alzheimer's disease[1].
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O-GlcNAcase-IN-5 | O-GlcNAcase-IN-5 (Compound 1) is a selective O-GlcNAcase inhibitor. O-GlcNAcase-IN-5 can prevent the enzyme from removing the O-GlcNAc modification on tau protein, thus avoiding excessive phosphorylation of tau protein. O-GlcNAcase-IN-5 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
