690693-02-8
690693-02-8
Chemical Structure
G43
- CAS No.: 690693-02-8
- Formula:C16H11N3O4S
- Molecular Weight:341.34
InChIKey: BTTXJIMSRRTAQM-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(S1)C=CC([N+]([O-])=O)=C2)NC3=CC=CC=C3C(N)=O
Biological Activity: G43 is a potent, selective glucosyltransferase inhibitor, with the Kd of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo, and can be used for dental caries study[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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G43 | 99.76% | G43 is a potent, selective glucosyltransferase inhibitor, with the Kd of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo, and can be used for dental caries study. | ||||||||||||||||||||
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References
- [1]. Zhang Q, et al. Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence. Sci Rep. 2017;7(1):5974. [Content Brief]
- [2]. Scaffa PMC, et al. The potential use of glycosyl-transferase inhibitors for targeted reduction of S. mutans biofilms in dental materials. Sci Rep. 2023;13(1):11889. [Content Brief]
Keywords
