69340-07-4
Chemical Structure
N,N'-Dinitrosopiperazine-d8
Synonym(s): 1,4-Dinitrosopiperazine-d8;DNP-d8
- CAS No.: 69340-07-4
- Formula:C4D8N4O2
- Molecular Weight:152.18
IUPAC Name: 1,4-dinitrosopiperazine-2,2,3,3,5,5,6,6-d8
InChIKey: WNSYEWGYAFFSSQ-SVYQBANQSA-N
SMILES: O=NN1C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C1([2H])[2H])N=O
Biological Activity: N,N'-Dinitrosopiperazine-d8 is the deuterium labeled N,N'-Dinitrosopiperazine[1]. N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine;DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N,N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568[2].
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N,N'-Dinitrosopiperazine-d8 | N,N'-Dinitrosopiperazine-d8 is the deuterium labeled N,N'-Dinitrosopiperazine. N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine;DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N,N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568. | |||||||||||||||||||||
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N,N'-Dinitrosopiperazine | 99.94% | N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N,N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Damao Huang, et al. Identification of Novel Signaling Components in N,N'-dinitrosopiperazine-mediated Metastasis of Nasopharyngeal Carcinoma by Quantitative Phosphoproteomics. BMC Cancer. 2014 Apr 5;14:243. [Content Brief]
