702697-89-0
Chemical Structure
Chitin synthase-IN-16
- CAS No.: 702697-89-0
- Formula:C22H25N5O4S2
- Molecular Weight:487.60
InChIKey: SPAXJHJEGKAXSM-GFMRDNFCSA-N
SMILES: O=S(N1CCOCC1)(C2=CC(/C(C(N3C)=O)=N/NC(NC4=CC=C(CC)C=C4)=S)=C3C=C2)=O
Biological Activity: Chitin synthase-IN-16 is a competitive Chitin synthase 2 inhibitor with an IC50 of 20.89 μM against CaChs2. Chitin synthase-IN-16 synergistically enhances the activity of Fluconazole (HY-B0101) against Fluconazole-tolerant Candida albicans. Chitin synthase-IN-16 can be used for research on invasive fungal infections[1].
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Chitin synthase-IN-16 | Chitin synthase-IN-16 is a competitive Chitin synthase 2 inhibitor with an IC50 of 20.89 μM against CaChs2. Chitin synthase-IN-16 synergistically enhances the activity of Fluconazole (HY-B0101) against Fluconazole-tolerant Candida albicans. Chitin synthase-IN-16 can be used for research on invasive fungal infections. | |||||||||||||||||||||
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