70695-02-2
Chemical Structure
Nargenicin A1
- CAS No.: 70695-02-2
- Formula:C28H37NO8
- Molecular Weight:515.60
IUPAC Name: (3R,4S,7S,8aS,10aR,11R,12R,13R,14R,14aS,14bS,E)-14-hydroxy-4-((R)-1-hydroxyethyl)-7-methoxy-1,3,13-trimethyl-6-oxo-3,4,6,7,8,8a,10a,11,12,13,14,14a-dodecahydro-11,14b-epoxynaphtho[2,1-e]oxecin-12-yl 1H-pyrrole-2-carboxylate
InChIKey: YEUSSARNQQYBKH-SIMZXIQRSA-N
SMILES: C/C([C@]12O[C@@H]([C@@H]([C@@H]([C@H]([C@]32[H])O)C)OC(C4=CC=CN4)=O)[C@]3([H])C=C[C@]1([H])C[C@@H]5OC)=C\[C@H]([C@]([H])(OC5=O)[C@H](O)C)C
Biological Activity: Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia[1].
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Nargenicin A1 | Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia. | |||||||||||||||||||||
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