Nargenicin A1
Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 70695-02-2
- Formula: C28H37NO8
- Molecular Weight:515.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 70695-02-2
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Molecular Weight 515.60
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Formula C28H37NO8
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SMILES
C/C([C@]12O[C@@H]([C@@H]([C@@H]([C@H]([C@]32[H])O)C)OC(C4=CC=CN4)=O)[C@]3([H])C=C[C@]1([H])C[C@@H]5OC)=C\[C@H]([C@]([H])(OC5=O)[C@H](O)C)C
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Structure Classification
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Initial Source
Nocardia sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Da Hye Kwon, et al. Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway. EXCLI J. 2021 May 28;20:968-982. [Content Brief]
[2]. Dhakal D, et al. Characterization of Tailoring Steps of Nargenicin A1 Biosynthesis Reveals a Novel Analogue with Anticancer Activities. ACS Chem Biol. 2020 Jun 19;15(6):1370-1380. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nargenicin A1 Related Classifications
HY-123121 Related Classifications
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