71129-71-0
Chemical Structure
(20S)-18,20-Epoxydigitoxigenin α-L-thvetoside
- CAS No.: 71129-71-0
- Formula:C30H46O9
- Molecular Weight:550.68
InChIKey: SAHFSRBBUCJJGW-YLJAROJLSA-N
SMILES: O[C@@]12[C@]3(CC[C@@]4([H])[C@@]2([H])CC[C@@]5([H])[C@@]4(CC[C@@H](C5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)O)C)[C@@](CC1)([H])[C@@]7(CC(OC7)=O)OC3
Biological Activity: (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside is a cardenolide glycoside found in the bark of Thevetia peruviana. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside is a tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) resistance-overcoming agent. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside synergistically sensitizes TRAIL-resistant gastric adenocarcinoma cells to TRAIL, reducing cell viability when combined with TRAIL. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside can be used for the research of human gastric adenocarcinoma[1].
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(20S)-18,20-Epoxydigitoxigenin α-L-thvetoside | (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside is a cardenolide glycoside found in the bark of Thevetia peruviana. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside is a tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) resistance-overcoming agent. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside synergistically sensitizes TRAIL-resistant gastric adenocarcinoma cells to TRAIL, reducing cell viability when combined with TRAIL. (20S)-18,20-Epoxydigitoxigenin α-L-thvetoside can be used for the research of human gastric adenocarcinoma. | |||||||||||||||||||||
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