7195-27-9
7195-27-9
Chemical Structure
Mefruside
- CAS No.: 7195-27-9
- Formula:C13H19ClN2O5S2
- Molecular Weight:382.88
IUPAC Name: 4-chloro-N1-methyl-N1-((2-methyltetrahydrofuran-2-yl)methyl)benzene-1,3-disulfonamide
InChIKey: SMNOERSLNYGGOU-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C(S(=O)(N)=O)=C1)Cl)(N(CC2(OCCC2)C)C)=O
Biological Activity: Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension[1][2].
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Mefruside | 99.9% | Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension. | ||||||||||||||||||||
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Mefruside-d3 | Mefruside-d3 is the deuterium labeled Mefruside. | |||||||||||||||||||||
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References
- [1]. Häussinger D, et al. Liver carbonic anhydrase and urea synthesis. Hepatology. 1988 Mar-Apr;8(2):435. [Content Brief]
- [2]. Brogden RN, et al. Mefruside: a preliminary report of its pharmacological properties and therapeutic efficacy in oedema and hypertension. Drugs. 1974;7(6):419-25. [Content Brief]
Keywords
