733009-42-2
733009-42-2
Chemical Structure
EGFR-IN-198
- CAS No.: 733009-42-2
- Formula:C16H10Cl3FN4O
- Molecular Weight:399.63
IUPAC Name: 2-chloro-N-(4-((4,5-dichloro-2-fluorophenyl)amino)quinazolin-6-yl)acetamide
InChIKey: VBXDUSMRNQVJRO-UHFFFAOYSA-N
SMILES: O=C(NC=1C=CC2=NC=NC(NC=3C=C(Cl)C(Cl)=CC3F)=C2C1)CCl
Biological Activity: EGFR-IN-198 is a selective EGFR inhibitor with subnanomolar irreversible inhibitory activity against EGFR. EGFR-IN-198 covalently binds to the kinase domain of EGFR and inhibits its autophosphorylation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-198 | EGFR-IN-198 is a selective EGFR inhibitor with subnanomolar irreversible inhibitory activity against EGFR. EGFR-IN-198 covalently binds to the kinase domain of EGFR and inhibits its autophosphorylation. | |||||||||||||||||||||
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References
Keywords
