73423-35-5
Chemical Structure
MD 220661
- CAS. Nr.: 73423-35-5
- Formula:C17H17ClN2O3
- Molecular Weight:332.78
IUPAC Name: 5-(aminomethyl)-3-(4-((3-chlorobenzyl)oxy)phenyl)oxazolidin-2-one
InChIKey: MNXGEQXWGHAVJR-UHFFFAOYSA-N
SMILES: O=C1OC(CN1C2=CC=C(C=C2)OCC3=CC=CC(Cl)=C3)CN
Biological Activity: MD 220661 is a semicarbazide-sensitive amine oxidase (SSAO) and monoamine oxidase (MAO) inhibitor, and serves as a major metabolite of MD 240928 in rat brain. MD 220661 acts as a substrate for SSAO and exhibits reversible, selective MAO-B inhibition in rat tissues; in the absence of semicarbazide, its inhibitory potency against MAO-A activity decreases with prolonged pre-incubation time. MD 220661 is applicable to studies related to enzyme-catalyzed metabolism[1].
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MD 220661 | MD 220661 is a semicarbazide-sensitive amine oxidase (SSAO) and monoamine oxidase (MAO) inhibitor, and serves as a major metabolite of MD 240928 in rat brain. MD 220661 acts as a substrate for SSAO and exhibits reversible, selective MAO-B inhibition in rat tissues; in the absence of semicarbazide, its inhibitory potency against MAO-A activity decreases with prolonged pre-incubation time. MD 220661 is applicable to studies related to enzyme-catalyzed metabolism. | |||||||||||||||||||||
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