7412-78-4
7412-78-4
Chemical Structure
Glycyl-L-glutamic acid
Synonym(s): H-Gly-Glu-OH; Gly-Glu
- CAS 番号: 7412-78-4
- Formula:C7H12N2O5
- Molecular Weight:204.18
IUPAC Name: glycyl-L-glutamic acid
InChIKey: IEFJWDNGDZAYNZ-BYPYZUCNSA-N
SMILES: O=C(O)CC[C@@H](C(O)=O)NC(CN)=O
Biological Activity: Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2].
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Glycyl-L-glutamic acid | 99.82% | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration. | ||||||||||||||||||||
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References
- [1]. Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc Natl Acad Sci U S A. 1985 Aug;82(15):5213-7. [Content Brief]
- [2]. Yourick JJ, et al. Regeneration of acetylcholinesterase in clonal neuroblastoma-glioma hybrid NG108-15 cells after soman inhibition: effect of glycyl-L-glutamine. Cell Biol Toxicol. 1991 Jul;7(3):229-37. [Content Brief]
