744218-85-7
744218-85-7
Chemical Structure
SAM-315
Synonym(s): WAY-255315
- CAS No.: 744218-85-7
- Formula:C21H20N4O2S
- Molecular Weight:392.47
IUPAC Name: 3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole
InChIKey: FYOVZCDHYOEKDE-UHFFFAOYSA-N
SMILES: O=S(C1=NNC2=C1C=C(N3CCNCC3)C=C2)(C4=CC=CC5=C4C=CC=C5)=O
Biological Activity: SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6, with Ki and IC50 of 1.1 nM and 4.6 nM, respectively. SAM-315 significantly increases acetylcholine and glutamate release in hippocampus of the brain[1].
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SAM-315 | SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6, with Ki and IC50 of 1.1 nM and 4.6 nM, respectively. SAM-315 significantly increases acetylcholine and glutamate release in hippocampus of the brain. | |||||||||||||||||||||
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References
Keywords
