745033-86-7
745033-86-7
Chemical Structure
Antileishmanial agent-23
- CAS No.: 745033-86-7
- Formula:C20H17N3O4S2
- Molecular Weight:427.50
InChIKey: VMUIILLRSVYCCU-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=NCC(S2)CSC3=NN=C(C4=CC5=C(OCO5)C=C4)O3
Biological Activity: Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].
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Antileishmanial agent-23 | Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei. | |||||||||||||||||||||
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