748816-43-5
748816-43-5
Chemical Structure
AL-12180
- CAS No.: 748816-43-5
- Formula:C21H27ClO6
- Molecular Weight:410.89
IUPAC Name: (Z)-7-((2R,3S,4R)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-4-hydroxytetrahydrofuran-3-yl)hept-4-enoic acid
InChIKey: GLYAVTUPQOQHAD-MOBTWWNESA-N
SMILES: O=C(CC/C=C\CC[C@@H]1[C@H](OC[C@@H]1O)/C=C/[C@H](COC2=CC=CC(Cl)=C2)O)O
Biological Activity: AL-12180 is a potent and selective FP-receptor agonist with a Ki of 143 nM. AL-12180 stimulates the mobilization of intracellular Ca2+ in h-TM and h-CM cells with EC50s of 111 and 11 nM, respectively[1].
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AL-12180 | AL-12180 is a potent and selective FP-receptor agonist with a Ki of 143 nM. AL-12180 stimulates the mobilization of intracellular Ca2+ in h-TM and h-CM cells with EC50s of 111 and 11 nM, respectively. | |||||||||||||||||||||
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References
Keywords
