755002-90-5
755002-90-5
Chemical Structure
VU0134992
- CAS No.: 755002-90-5
- Formula:C20H31BrN2O2
- Molecular Weight:411.38
IUPAC Name: 2-(2-bromo-4-isopropylphenoxy)-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide
InChIKey: OTTDLWFVHQYRDA-UHFFFAOYSA-N
SMILES: O=C(NC1CC(C)(C)NC(C)(C)C1)COC2=CC=C(C(C)C)C=C2Br
Biological Activity: VU0134992 is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VU0134992 | 99.30% | VU0134992 is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV. | ||||||||||||||||||||
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References
Keywords
