75969-83-4
75969-83-4
Chemical Structure
11-Hydroxycanthin-6-one
- CAS No.: 75969-83-4
- Formula:C14H8N2O2
- Molecular Weight:236.23
IUPAC Name: 11-hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
InChIKey: KXFAUPPCQVBDBN-UHFFFAOYSA-N
SMILES: O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4O)C=C1
Biological Activity: 11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].
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11-Hydroxycanthin-6-one | 11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity. | |||||||||||||||||||||
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References
- [1]. Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3. [Content Brief]
- [2]. Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5(1):17-22. [Content Brief]
