76093-35-1

(R)-Nicardipine Chemical Structure
76093-35-1

Chemical Structure

(R)-Nicardipine

Synonym(s): (R)-YC-93 free base

  • CAS No.: 76093-35-1
  • Formula:C26H29N3O6
  • Molecular Weight:479.52

IUPAC Name: 3-(2-(benzyl(methyl)amino)ethyl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

InChIKey: ZBBHBTPTTSWHBA-XMMPIXPASA-N

SMILES: O=C(C1=C(C)NC(C)=C(C(OCCN(C)CC2=CC=CC=C2)=O)[C@@H]1C3=CC=CC([N+]([O-])=O)=C3)OC

Biological Activity: (R)-Nicardipine ((R)-YC-93 free base) is the less active R enantiomer of Nicardipine. Nicardipine (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure[1].

Cat. No. Product Name Purity Description Pricing
HY-12515C
(R)-Nicardipine 99.73% (R)-Nicardipine ((R)-YC-93 free base) is the less active R enantiomer of Nicardipine. Nicardipine (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure.
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HY-12515CS1
(R)-Nicardipine-d3 99.0% (R)-Nicardipine-d3 is the deuterium labeled R-Nicardipine (HY-12515C).
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References