765899-28-3
765899-28-3
Chemical Structure
BCRP-IN-1
- CAS No.: 765899-28-3
- Formula:C16H14N4O4
- Molecular Weight:326.31
IUPAC Name: 6,7-dimethoxy-N-(4-nitrophenyl)quinazolin-4-amine
InChIKey: IJPROWBQSHRNDZ-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1)[O-]
Biological Activity: BCRP-IN-1 (compound 48) is a potent inhibitor of breast cancer resistance protein (BCRP), with IC50s of 2.92 μM and 2.46 μM in Hoechst 33342 assay and Pheophorbide A assay, respectively[1].
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BCRP-IN-1 | BCRP-IN-1 (compound 48) is a potent inhibitor of breast cancer resistance protein (BCRP), with IC50s of 2.92 μM and 2.46 μM in Hoechst 33342 assay and Pheophorbide A assay, respectively. | |||||||||||||||||||||
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