769970-91-4
Chemical Structure
LY52
- CAS No.: 769970-91-4
- Formula:C22H24N4O6
- Molecular Weight:440.45
IUPAC Name: N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-(hydroxycarbamoyl)pyrrolidin-3-yl)nicotinamide
InChIKey: AKOSAZUQCGCWJD-IWDGFTLQSA-N
SMILES: O=C(N[C@@H]1CN([C@@H](C1)C(NO)=O)C(/C=C/C2=CC=C(C(OC)=C2)OC)=O)C3=CC=CN=C3
Biological Activity: LY52 is an MMP-2 and MMP-9 inhibitor. LY52 can significantly block the proteolytic activity of gelatinases, reducing the expression of MMP-2 and MMP-9 in SKOV3 cells, thereby inhibiting cell invasion. LY52 can also suppress the pulmonary metastasis of Lewis lung carcinoma cells in mice. LY52 may be used in cancer research[1].
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LY52 | LY52 is an MMP-2 and MMP-9 inhibitor. LY52 can significantly block the proteolytic activity of gelatinases, reducing the expression of MMP-2 and MMP-9 in SKOV3 cells, thereby inhibiting cell invasion. LY52 can also suppress the pulmonary metastasis of Lewis lung carcinoma cells in mice. LY52 may be used in cancer research. | |||||||||||||||||||||
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Keywords
