77-40-7
77-40-7
Chemical Structure
Bisphenol B
- CAS No.: 77-40-7
- Formula:C16H18O2
- Molecular Weight:242.31
IUPAC Name: 4,4'-(Butane-2,2-diyl)diphenol
InChIKey: HTVITOHKHWFJKO-UHFFFAOYSA-N
SMILES: CCC(C1=CC=C(O)C=C1)(C2=CC=C(O)C=C2)C
Biological Activity: Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisphenol B | 99.34% | Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties. | ||||||||||||||||||||
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Bisphenol B (Standard) | ≥98% | Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties. | ||||||||||||||||||||
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Bisphenol B-13C12 | Bisphenol B-13C12 is 13C labeled Bisphenol B. | |||||||||||||||||||||
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Bisphenol B-d8 | 98.89% | Bisphenol B-d8 is the deuterium labeled Bisphenol B (HY-W013935). Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC). Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models. | ||||||||||||||||||||
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Bisphenol A | 99.91% | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d6 | 99.04% | Bisphenol A-d6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-13C12 | 96.38% | Bisphenol A-13C12 is the 13C-labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Hexestrol | 99.79% | Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle. | ||||||||||||||||||||
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4-Cumylphenol | 99.70% | 4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes. | ||||||||||||||||||||
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Bisphenol E | 99.90% | Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent. | ||||||||||||||||||||
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(Rac)-Hexestrol | (Rac)-Hexestrol is the racemic form of Hexestrol (HY-B1662). Hexestrol is a synthetic non-steroidal estrogen. (Rac)-Hexestrol usually appears in deuterated form and is used as an internal standard for precise quantitative analysis in analytical chemistry. | |||||||||||||||||||||
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3-Chlorobisphenol A | 95.19% | 3-Chlorobisphenol A, a chlorinated derivatives of bisphenol A, is an endocrine-disrupting compound. It binds to estrogen receptors, causing disorders in hormone signaling pathways. Bisphenol A is an industrial chemical used in the production of polycarbonate plastics and epoxy resin. | ||||||||||||||||||||
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Bisphenol AF-13C12 | Bisphenol AF-13C12 is an isotopic label of Bisphenol AF. Bisphenol AF is used in polycarbonate plastic and epoxy resin manufacturing. Bisphenol AF can significantly increase intracellular ROS levels. | |||||||||||||||||||||
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Bisphenol A-13C2 | Bisphenol A-13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | |||||||||||||||||||||
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References
- [1]. Serra H, et al. Evidence for Bisphenol B Endocrine Properties: Scientific and Regulatory Perspectives. Environ Health Perspect. 2019 Oct;127(10):106001. [Content Brief]
- [2]. Grumetto, L., et al., (2008). Determination of bisphenol a and bisphenol B residues in canned peeled tomatoes by reversed-phase liquid chromatography. Journal of agricultural and food chemistry, 56(22), 10633–10637. [Content Brief]
- [3]. Cao, L. Y., et al., (2017). Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway. Environmental science & technology, 51(19), 11423–11430. [Content Brief]
