Bisphenol B (Standard)
Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties.
For research use only. We do not sell to patients.
- CAS No.: 77-40-7
- Formula: C16H18O2
- Molecular Weight:242.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 77-40-7
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Molecular Weight 242.31
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Formula C16H18O2
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SMILES
CCC(C1=CC=C(O)C=C1)(C2=CC=C(O)C=C2)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Serra H, et al. Evidence for Bisphenol B Endocrine Properties: Scientific and Regulatory Perspectives. Environ Health Perspect. 2019 Oct;127(10):106001. [Content Brief]
[2]. Grumetto, L., et al., (2008). Determination of bisphenol a and bisphenol B residues in canned peeled tomatoes by reversed-phase liquid chromatography. Journal of agricultural and food chemistry, 56(22), 10633-10637. [Content Brief]
[3]. Cao, L. Y., et al., (2017). Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway. Environmental science & technology, 51(19), 11423-11430. [Content Brief]
[4]. Ullah, A., (2018). Bisphenol A and its analogs bisphenol B, bisphenol F, and bisphenol S: Comparative in vitro and in vivo studies on the sperms and testicular tissues of rats. Chemosphere, 209, 508-516. [Content Brief]
[5]. Ullah, A., et al., (2018). Impact of low-dose chronic exposure to bisphenol A and its analogue bisphenol B, bisphenol F and bisphenol S on hypothalamo-pituitary-testicular activities in adult rats: A focus on the possible hormonal mode of action. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 121, 24-36. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bisphenol B (Standard) Related Classifications
HY-W013935R Related Classifications
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