77263-06-0
Chemical Structure
Erythrabyssin II
- CAS No.: 77263-06-0
- Formula:C25H28O4
- Molecular Weight:392.49
IUPAC Name: (6aR,11aR)-2,10-bis(3-methylbut-2-en-1-yl)-6a,11a-dihydro-6H-benzofuro[3,2-c]chromene-3,9-diol
InChIKey: LDKAMVCGTURXMH-CPJSRVTESA-N
SMILES: OC1=C(C/C=C(C)\C)C=C2[C@@](OC3=C(C/C=C(C)\C)C(O)=CC=C34)([H])[C@@]4([H])COC2=C1
Biological Activity: Erythrabyssin II (EL-19) is a potent late-stage autophagy inhibitor that blocks the fusion of autophagosome and lysosome. Erythrabyssin II leads to the accumulation of autophagic substrates and does not impair lysosomal pH or lysosomal enzyme activity. Erythrabyssin II suppresses ovarian cancer organoid activity and induces apoptosis. Erythrabyssin II can be used for the study of ovarian cancer[1].
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Erythrabyssin II | Erythrabyssin II (EL-19) is a potent late-stage autophagy inhibitor that blocks the fusion of autophagosome and lysosome. Erythrabyssin II leads to the accumulation of autophagic substrates and does not impair lysosomal pH or lysosomal enzyme activity. Erythrabyssin II suppresses ovarian cancer organoid activity and induces apoptosis. Erythrabyssin II can be used for the study of ovarian cancer. | |||||||||||||||||||||
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Keywords
