7755-28-4
Chemical Structure
AY 17605
- CAS. Nr.: 7755-28-4
- Formula:C25H36O5
- Molecular Weight:416.56
IUPAC Name: (3S,5R,8R,9S,10S,13R,14S,17S)-14-hydroxy-10,13-dimethyl-17-(2-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate
InChIKey: YIGNMQYFYCCUME-KKBDMWJISA-N
SMILES: O[C@@]12[C@@](C)([C@H](CC1)C=3C(=O)OCC3)CC[C@]4([C@]2(CC[C@]5([C@]4(C)CC[C@H](OC(C)=O)C5)[H])[H])[H]
Biological Activity: AY 17605 is a nucleoside-3':5'-monophosphate phosphodiesterase (Phosphodiesterase) inhibitor that blocks cAMP hydrolysis through non-competitive inhibition, thereby elevating intracellular cAMP levels. AY 17605 can be used in studies related to cardiotonic activity[1][2].
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AY 17605 | AY 17605 is a nucleoside-3':5'-monophosphate phosphodiesterase (Phosphodiesterase) inhibitor that blocks cAMP hydrolysis through non-competitive inhibition, thereby elevating intracellular cAMP levels. AY 17605 can be used in studies related to cardiotonic activity. | |||||||||||||||||||||
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References
- [1]. Lippmann W. Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds. Experientia. 1974 Mar 15;30(3):237-9.
- [2]. Balogun RA. Amino acids in the excreta of the tsetse fly, Glossina palpalis. Experientia. 1974 Mar 15;30(3):239-40.
