793726-84-8
Chemical Structure
BIBU1361
- CAS No.: 793726-84-8
- Formula:C22H27ClFN7
- Molecular Weight:443.95
IUPAC Name: N-(3-chloro-4-fluorophenyl)-6-(4-((diethylamino)methyl)piperidin-1-yl)pyrimido[5,4-d]pyrimidin-4-amine
InChIKey: JUGSLZCFNSTKBN-UHFFFAOYSA-N
SMILES: CCN(CC1CCN(C2=NC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=N2)CC1)CC
Biological Activity: BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
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BIBU1361 | BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6. | |||||||||||||||||||||
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Keywords