799279-80-4
799279-80-4
Chemical Structure
Sofiniclin
Synonym(s): ABT 894
- CAS No.: 799279-80-4
- Formula:C10H11Cl2N3
- Molecular Weight:244.13
IUPAC Name: (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane
InChIKey: MBQYQLWSBRANKQ-IMTBSYHQSA-N
SMILES: ClC1=C(Cl)C=C(N2C[C@]3([H])CN[C@]3([H])C2)C=N1
Biological Activity: Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR), is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Sofiniclin | 99.63% | Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR), is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.71
HY-14824ASofinicline benzenesulfonate -
Similarity Score 0.62
HY-116149A-424274 -
Similarity Score 0.60
HY-183666NS3956 -
Similarity Score 0.58
HY-W027787Aripiprazole impurity 9 -
Similarity Score 0.57
HY-124540B(Rac)-ABT-202 dihydrochloride -
Similarity Score 0.56
HY-W979493TC-2216 -
Similarity Score 0.55
HY-W3514281-(3-Chloro-4-fluorophenyl)piperazine hydrochloride -
Similarity Score 0.55
HY-W0011982,3,5-Trichloropyridine -
Similarity Score 0.55
HY-124540ABT-202 -
Explore the MedChemAI to find more analogs
References
- [1]. Zhang D, et al. ABT-089 and ABT-894 reduce levodopa-induced dyskinesias in a monkey model of Parkinson's disease. Mov Disord. 2014 Apr;29(4):508-17. [Content Brief]
- [2]. Zhang D, ET AL. α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage. Mov Disord. 2015 Dec;30(14):1901-11. [Content Brief]
