80261-18-3
80261-18-3
Chemical Structure
NSC177365
Synonym(s): NSC 1
- CAS 番号: 80261-18-3
- Formula:C23H23N7O4S
- Molecular Weight:493.54
IUPAC Name: 3-guanidino-N-(4-((3-nitroacridin-9-yl)amino)phenyl)propane-1-sulfonamide
InChIKey: ZBXXIEYBGSMVKQ-UHFFFAOYSA-N
SMILES: O=S(CCCNC(N)=N)(NC1=CC=C(NC2=C(C=CC([N+]([O-])=O)=C3)C3=NC4=CC=CC=C42)C=C1)=O
Biological Activity: NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent[1].
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NSC177365 | NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent. | |||||||||||||||||||||
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