8064-60-6
Chemical Structure
Primulin
Synonym(s): Primuline
- CAS No.: 8064-60-6
- Formula:C21H14N3NaO3S3
- Molecular Weight:475.54
IUPAC Name: 2-nitrobenzenesulfonic acid
InChIKey: ZAXBCXVACRXRQZ-UHFFFAOYSA-N
SMILES: O=S(C1=C(C)C=CC2=C1SC(C3=CC(SC(C4=CC=C(N)C=C4)=N5)=C5C=C3)=N2)(O[Na])=O
Biological Activity: Primulin is a versatile fluorescent dye and bioactive compound widely used in analytical, biological, botanical and virological studies. Primulin acts as a versatile stain that labels plant cell walls and differentiates live and dead spermatozoa via distinct fluorescence patterns. Primulin exhibits strong albumin‑binding capacity. Primulin acts as a retrograde axonal tracer in neurobiological investigations. Primulin and its derivatives inhibit HCV NS3, block dengue virus NS3-mediated ATP hydrolysis, and disrupt HCV replicase assembly[1][2][3].
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Primulin | Primulin is a versatile fluorescent dye and bioactive compound widely used in analytical, biological, botanical and virological studies. Primulin acts as a versatile stain that labels plant cell walls and differentiates live and dead spermatozoa via distinct fluorescence patterns. Primulin exhibits strong albumin‑binding capacity. Primulin acts as a retrograde axonal tracer in neurobiological investigations. Primulin and its derivatives inhibit HCV NS3, block dengue virus NS3-mediated ATP hydrolysis, and disrupt HCV replicase assembly. | |||||||||||||||||||||
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References
- [1]. Ndjomou J, et al. Fluorescent primuline derivatives inhibit hepatitis C virus NS3-catalyzed RNA unwinding, peptide hydrolysis and viral replicase formation. Antiviral Res. 2012;96(2):245-255. [Content Brief]
- [2]. Enerbäck L, et al. Cytophotometric quantification of retrograde axonal transport of a fluorescent tracer (primuline) in mouse facial neurons. Brain Res. 1980;186(1):21-32. [Content Brief]
- [3]. Richter G, et al. The reaction between phosphatidylethanolamines and HOCl investigated by TLC: fading of the dye primuline is induced by dichloramines. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 May 15;867(2):233-7. [Content Brief]
