82190-91-8
82190-91-8
Chemical Structure
Flufylline
Synonym(s): Sgd 195/78
- CAS No.: 82190-91-8
- Formula:C21H24FN5O3
- Molecular Weight:413.45
IUPAC Name: 7-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: PMEYQPKJAPXGPS-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C)C(N1C)=O)N=CN2CCN3CCC(CC3)C(C4=CC=C(C=C4)F)=O
Biological Activity: Flufylline shows antihypertensive properties in spontaneously hypertensive rats and display antagonism towards 5-HT receptors in various animal models. Flufylline can be used for cardiovascular disease research[1].
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Flufylline | Flufylline shows antihypertensive properties in spontaneously hypertensive rats and display antagonism towards 5-HT receptors in various animal models. Flufylline can be used for cardiovascular disease research. | |||||||||||||||||||||
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References
- [1]. Korstanje C, et al. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38(5):374-9. [Content Brief]
Keywords
