83730-53-4
83730-53-4
Chemical Structure
L-Buthionine-(S,R)-sulfoximine
Synonym(s): L-Buthionine sulfoximine; L-BSO
- CAS No.: 83730-53-4
- Formula:C8H18N2O3S
- Molecular Weight:222.31
IUPAC Name: (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid
InChIKey: KJQFBVYMGADDTQ-CVSPRKDYSA-N
SMILES: N[C@H](C(O)=O)CCS(CCCC)(=O)=N
Biological Activity: L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
L-Buthionine-(S,R)-sulfoximine | 99.95% | L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
L-Buthionine-(S,R)-sulfoximine (Standard) | ≥98% | L-Buthionine-(S,R)-sulfoximine (Standard) is the analytical standard of L-Buthionine-(S,R)-sulfoximine (HY-106376A). This product is intended for research and analytical applications. L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
