841255-57-0
Chemical Structure
c-RGD-SH
- CAS No.: 841255-57-0
- Formula:C29H43N9O8S
- Molecular Weight:677.77
IUPAC Name: 2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-8-(4-(2-mercaptoacetamido)butyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
InChIKey: JJNLPMZVOCVPDR-BURNTYAHSA-N
SMILES: O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CS)=O)[C@H]1CC2=CC=CC=C2
Biological Activity: c-RGD-SH is a ligand for integrin αvβ3 (Integrin αvβ3). Conjugation of c-RGD-SH with core-crosslinked polymeric micelles (CCPM) enables the synthesis of a bimodal nanoprobe, which can be labeled with Cy7 and 111In for SPECT and NIRF imaging of tumors[1].
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c-RGD-SH | c-RGD-SH is a ligand for integrin αvβ3 (Integrin αvβ3). Conjugation of c-RGD-SH with core-crosslinked polymeric micelles (CCPM) enables the synthesis of a bimodal nanoprobe, which can be labeled with Cy7 and 111In for SPECT and NIRF imaging of tumors. | |||||||||||||||||||||
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