841302-51-0
Chemical Structure
BMS-538305 hydrochloride
- CAS No.: 841302-51-0
- Formula:C17H27ClN2O2
- Molecular Weight:326.86
IUPAC Name: (S)-2-amino-1-((1S,5R)-2-azabicyclo[3.1.0]hexan-2-yl)-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)ethan-1-one hydrochloride
InChIKey: LQQSFVABLOCZDJ-JXKDNGTOSA-N
SMILES: O=C(N1[C@@H]2[C@H](CC1)C2)[C@H]([C@@]34C[C@@](C[C@H](C[C@H]5C4)C3)(C5)O)N.Cl
Biological Activity: BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
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BMS-538305 hydrochloride | BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis. | |||||||||||||||||||||
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Keywords
