842-01-3
842-01-3
Chemical Structure
4-Phenyl-7,8-dihydroxycoumarin
- CAS No.: 842-01-3
- Formula:C15H10O4
- Molecular Weight:254.24
IUPAC Name: 7,8-dihydroxy-4-phenyl-2H-chromen-2-one
InChIKey: JRVIIPJSVKTPBK-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)C3=CC=C(O)C(O)=C3O1
Biological Activity: 4-Phenyl-7,8-dihydroxycoumarin is a coumarin-based non-nitro catechol-type COMT inhibitor with an IC50 of 1.8 μM against rat S-COMT. 4-Phenyl-7,8-dihydroxycoumarin can be used in studies on the binding mechanism of COMT inhibitors and Parkinson's disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Phenyl-7,8-dihydroxycoumarin | 99.35% | 4-Phenyl-7,8-dihydroxycoumarin is a coumarin-based non-nitro catechol-type COMT inhibitor with an IC50 of 1.8 μM against rat S-COMT. 4-Phenyl-7,8-dihydroxycoumarin can be used in studies on the binding mechanism of COMT inhibitors and Parkinson's disease. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-W240322PSF-IN-1 -
Similarity Score 0.82
HY-N4287Nordalbergin -
Similarity Score 0.81
HY-W2071957-Hydroxy-4-phenylcoumarin -
Similarity Score 0.78
HY-W013372R7,8-Dihydroxyflavone (Standard) -
Similarity Score 0.78
HY-116068DW532 -
Similarity Score 0.78
HY-130259LC3-mHTT-IN-AN2 -
Similarity Score 0.77
HY-N8347Dalbergin -
Similarity Score 0.70
HY-1315863,7-Dihydroxyflavone -
Similarity Score 0.70
HY-173177PSF-IN-2 -
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