84304-92-7
84304-92-7
Chemical Structure
Rabdosin B
- CAS No.: 84304-92-7
- Formula:C24H32O8
- Molecular Weight:448.51
IUPAC Name: ((1R,2S,4a'S,5'S,6R,7'S,9a'S)-2-acetoxy-5'-hydroxy-5,5-dimethyl-8'-methylene-1',9'-dioxohexahydro-1'H,3'H-spiro[cyclohexane-1,4'-[7,9a]methanocyclohepta[c]pyran]-6-yl)methyl acetate
InChIKey: LUXJXSFHXOVGTA-DUAAMXSASA-N
SMILES: CC(OC[C@H](C1(C)C)[C@]([C@H](CC1)OC(C)=O)(COC2=O)[C@@]3([H])[C@]2(C(C4=C)=O)C[C@@]4([H])C[C@@H]3O)=O
Biological Activity: Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings[1][2].
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Rabdosin B | Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings. | |||||||||||||||||||||
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References
- [1]. Lan Ding, et al. Regulation of cell division and growth in roots of Lactuca sativa L. seedlings by the Ent-Kaurene diterpenoid rabdosin B. J Chem Ecol. 2010 May;36(5):553-63. [Content Brief]
- [2]. Lan Ding, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25(15):1402-11. [Content Brief]
