847453-47-8
Chemical Structure
ANA-975
- CAS No.: 847453-47-8
- Formula:C14H16N4O7S
- Molecular Weight:384.36
IUPAC Name: (2R,3R,4R,5R)-2-(5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate
InChIKey: ZWELIJXAKMASLK-UGKPPGOTSA-N
SMILES: O=C1SC2=CN=C(N)N=C2N1[C@H]3[C@@H]([C@@H]([C@@H](CO)O3)OC(C)=O)OC(C)=O
Biological Activity: ANA975, 5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one derivative, is an oral prodrug of the TLR-7 agonist Isatoribine (HY-13655A). ANA975 is converted to Isatoribine via a combined mechanism of hydrolysis by esterases and oxidation by aldehyde oxidase. ANA975 can be used in the research of hepatitis C virus infection[1].
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ANA-975 | ANA975, 5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one derivative, is an oral prodrug of the TLR-7 agonist Isatoribine (HY-13655A). ANA975 is converted to Isatoribine via a combined mechanism of hydrolysis by esterases and oxidation by aldehyde oxidase. ANA975 can be used in the research of hepatitis C virus infection. | |||||||||||||||||||||
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